| 100 Meter Dash | 12.20 | Taylor Hooks | Regional Meet | 2019 | |
| 200 Meter Dash | 24.92 | Taylor Hooks | Regional Meet | 2016 | |
| 400 Meter Dash | 55.75 | Sher Champe | State Meet | 2013 | |
| 800 Meter Run | 2:10.05 | Theresa Feldkamp | State Meet | 2001 | |
| 1600 Meter Run | 4:54.23 | Amy McKinley | State Meet | 1993 | |
| 3200 Meter Run | 10:42.5 | Amy McKinley | Regional Meet | 1993 | |
| 100 Meter Hurdles | 14.2 | Kristi Keplinger | Vermillion Invitational | 1987 | |
| 300 Meter Hurdles | 43.73 | Sara Moore | SWC Meet | 2013 | |
| 400 Meter Hurdles | 1:21.38 | Madison Reynolds | Beach Run Invitational | 2015 | |
| 2000 M Steeplechase | 8:19.20 | Kayla Snowden | Tri-Cities Classic | 2018 | |
| 4 x 100 M. Relay | 48.71 | Taylor Hooks, Audrey Fayer, Brooke Armbruster, Madison Reynolds | Regional Meet | 2016 | |
| 4 x 200 M. Relay | 1:41.40 | Brianna Shagovac, Lindsay Sands, Becky Stuckart, Sher Champe | State Meet | 2013 | |
| 4 x 400 M. Relay | 3:52.94 | Lindsay Sands, Alexis Szivan, Brianna Shagovac, Sher Champe | State Meet | 2013 | |
| 4 x 800 M. Relay | 9:24.65 | Alexis Szivan, Cara Giannuzzi, Megan Parker, Sher Champe | Regional Meet | 2014 | |
| 4 x 1600 M. Relay | 22:06.6 | Heather Skeeles, Kelly Nye, Jenny Luca, Christine Thompson | Westlake Relays | 1997 | |
| Sprint Medley | 1:49.63 | Bakita Hill, Becki Stuckart, Briana Shagovac, Lindsey Sands | Berea Relays | 2013 | |
| Distance Medley | 12:30.97 | Sher Champe, Undrea Ballard, Alexis Szivan, Megan Parker | Berea Relays | 2014 | |
| Shuttle Hurd. (low) | 1:06.56 | Erin Kasper, Amber Slavik, Gaby Northeim, Sara Moore | Berea Relays | 2013 | |
| Shuttle Hurd. (high) | 1:09.10 | Erin Kasper, Amber Slavik, Gaby Northeim, Sara Moore | Comet Relays | 2013 | |
| High Jump | 5’6 | Erin Kasper | SWC Meet | 2013 | |
| 5’6 | Chaley Younkin | SWC Meet | 2021 | ||
| High Jump Relay | 15’4 | Erin Kasper, Amber Slavik, Madison Reynolds | Comet Relays | 2013 | |
| Long Jump | 17’11 | Madison Reynolds | Vs. Midview-N. Olmsted | 2016 | |
| Long Jump Relay | 49′ 1/4 | Madison Reynolds, Audrey Fayer, Gracen Siegenthaler | Comet Relays | 2008 | |
| Triple Jump | 32’11 1/2 | Gabriela Giannuzzi | Tri-Cities Classic | 2018 | |
| Shot Put | 40’10 1/2 | Emily King | Regional Meet | 2018 | |
| Shot Put Relay | 96’10 1/2 | Abby Burgdorf, Katie Schuster, Shannon Theobald | Comet Relay | 2009 | |
| Discus | 127’7 | Amy Lackner | State Meet | 1989 | |
| Discus Relay | 309’5 | Lori Betchker, Shannon Mixon, Nicole Richardson | Vs. Olm. Falls-Westlake | 1999 | |
| Pole Vault | 11’6 | Sydney Walker | State Meet | 2019 | |
| Pole Vault Relay (2) | 20’6 | Sydney Walker, Allison Takacs | Comet Relays | 2018 | |
| Pole Vault Relay (3) | 24’0 | Caitlin Camp, Kayla Nunez, Alex Forneris | Comet Relays | 2011 | |
| Amherst Girls Indoor School Records | |||||
| 60 Meter Dash | 7.60 | Taylor Hooks | State Indoor Meet | 2019 | |
| 60 Meter Hurdles | 9.25 | Sara Moore | State Indoor Meet | 2013 | |
| 9.25 | Michal McFall | State Indoor Meet | 2020 | ||
| 200 Meter Dash | 25.24 | Taylor Hooks | State Indoor Meet | 2019 | |
| 400 Meter Dash | 58.73 | Undrea Ballard | State Indoor Meet | 2016 | |
| 800 Meter Run | 2:14.70 | Theresa Feldkamp | Nike Indoor Classic | 2000 | |
| 1600 Run | 5:14.9 | Christine Thompson | Berea Kiwanis Indoor | 1997 | |
| 3200 Run | 11:25.11 | Cassie Vince | State Indoor Meet | 2013 | |
| 4×200 Meter Relay | 1:45.95 | Taylor Hooks, Tori Kubasak, Leah Drost, Gracen Siegenthaler | State Indoor Meet | 2018 | |
| 4×400 Meter Relay | 4:09.15 | Undrea Ballard, Alexis Szivan, Lauren Sturgeon, Gracen Siegenthaller | State Indoor Meet | 2015 | |
| 4×800 Meter Relay | 9:54.54 | Cassie Vince, Riley Schenk, Lauren Sturgeon, Alexis Szivan | State Indoor Meet | 2013 | |
| Long Jump | 17’3 | Madison Reynolds | State Indoor Meet | 2016 | |
| High Jump | 5’6 | Erin Kasper | Akron Indoor | 2013 | |
| Triple Jump | 33’1 | Gabriela Giannuzzi | State Indoor Meet | 2018 | |
| Shot Put | 36’10 1/2 | Emily King | Oberlin Indoor 4 | 2018 | |
| Weight Throw | 44’0 1/4 | Emily King | State Indoor Meet | 2018 | |
| Pole Vault | 11’0 | Sydney Walker | State Indoor Meet | 2018 | |